Investors

New Enterprise Associates, Inc. (NEA)

NEA is a leading venture capital and growth equity firm focused on helping entrepreneurs build transformational businesses across multiple stages, sectors and geographies. With approximately $11 billion in committed capital, NEA invests in information technology, healthcare and energy technology companies at all stages in a company's lifecycle, from seed stage through IPO. Since the firm's founding in 1978, NEA's experienced management team has invested in over 650 companies, of which more than 165 have gone public and more than 265 have been acquired. In the U.S., NEA has two offices in the Washington, D.C. metropolitan area and one in Menlo Park, California. In addition, New Enterprise Associates (India) Pvt. Ltd. has offices in Bangalore and Mumbai, India and New Enterprise Associates (Beijing), Ltd. has offices in Beijing and Shanghai, China. For additional information, visit www.nea.com.

OrbiMed

OrbiMed is a leading investment firm dedicated exclusively to the healthcare sector, with approximately $6 billion in assets under management as of September 30, 2012. With offices in New York City, San Francisco, Shanghai, Mumbai and Herzliya, OrbiMed invests across the spectrum of healthcare companies on a worldwide basis. OrbiMed seeks to be a capital provider of choice, bringing the global resources required to be an excellent long‐term partner for building world-class healthcare companies. www.orbimed.com.

The Aurora Funds

The Aurora Funds is a family of venture capital funds committed to providing resources to help early stage healthcare and information technology companies reach their full potential.

Aurora's investment team has the experience, strategic relationships and capital to help companies accelerate their growth and gain a strong competitive advantage in their market space. Since its founding in 1994, Aurora has invested in over 60 portfolio companies, resulting in five IPOs and eight M&A transactions.

Osage University Partners

Osage University Partners is a venture capital fund that invests exclusively in spinouts derived from a network of 46 affiliated research institutions. www.osagepartners.com/partners.html